Chronic Obstructive Pulmonary Disease (COPD) - MSD Manuals

cop4dWhat causes COPD? Damage to your lungs from smoking is the most common cause of COPD. Other causes include: Alpha-1 antitrypsin deficiency (alpha-1), a geneticCOPD can cause coughing that produces large amounts of a slimy substance called mucus .It can also cause breathing problems, shortness of breath, chest thtness,